It saw much of its service in the jungles of Vietnam, used as a suppressive machine gun. Even though the M240 is more accurate and has a faster rate of fire, the M60(E3/E4) weighs only 8.5kg, making it favorable for special operations.
It also played a background role during the Battle of Mogadishu in Somalia in the mid 90s for the Army Rangers. The M60 was used in Kuwait and Iraq in Operation Desert Storm. It is also used (albeit rarely, as it has been almost completely phased out in favor of the M240) in some parts of Iraq and Afghanistan today.